
Yaws is a chronic, contagious skin and bone infection that primarily affects children in areas of poverty with limited access to healthcare. Though preventable and treatable, this neglected tropical disease (NTD) continues to cause significant suffering in communities worldwide, including in Liberia, where Effect Hope has been working in partnership with the Ministry of Health since 2012.
For more details on Yaws, including transmission, symptoms, and treatment, visit the World Health Organization’s fact sheet. According to the WHO, Yaws is targeted for eradication, yet thousands of cases persist due to challenges in diagnosis and treatment accessibility.
Understanding Yaws
Yaws is caused by the bacterium Treponema pertenue, which spreads through direct skin contact, particularly among children under 15 years old. The disease begins with a small, painless sore that gradually enlarges. If left untreated, Yaws can progress to affect bones and joints, leading to severe pain, deformities, and lifelong disability.
Although Yaws is not fatal, its disfiguring effects and associated stigma can have devastating social and economic consequences for those affected. Without timely diagnosis and treatment, the infection can severely impact mobility, education, and employment opportunities.
How is Yaws Transmitted?
Yaws spreads through direct skin-to-skin contact with an infected person, particularly in warm, humid environments where the bacteria thrive. Poor sanitation, overcrowding, and limited healthcare access contribute to the continued transmission of the disease.
Unlike other infectious diseases, Yaws is not spread through insects or contaminated water. Its high prevalence in certain regions highlights the urgent need for community-based interventions to halt its transmission.
Symptoms and Progression
- Early Stage: A single lesion, often mistaken for a bug bite or common sore, appears on the skin. This lesion may heal on its own but can leave behind scarring.
- Secondary Stage: If untreated, multiple sores can develop, often accompanied by swelling of the bones and joints, leading to pain and restricted movement.
- Late Stage: In severe cases, untreated Yaws can result in permanent disfigurement and disability, affecting the face, limbs, and bones.
Diagnosis and Treatment
Yaws is diagnosed clinically based on symptoms and confirmed through laboratory tests such as rapid serological tests and PCR (Polymerase Chain Reaction) analysis.
Treatment is simple and highly effective: a single oral dose of the antibiotic Azithromycin can cure the disease and stop transmission. In areas where treatment campaigns have been successfully implemented, cases have significantly declined.
A Story of Hope: Fighting Yaws in Liberia
In November of 2024, Liberia faced a growing crisis as cases of Yaws surged in remote communities, leaving thousands at risk. Thanks to the incredible generosity of our supporters and a $30,000 matching grant from the Anesvad Foundation, we raised over $61,000 to take action! In partnership with Liberia’s Ministry of Health, we mobilized community-based efforts to combat the outbreak. Our teams conducted health screenings in 44 remote communities, identifying and treating hundreds of people with Yaws, many of them children. Mobile response teams provided immediate treatment and trained local healthcare workers to diagnose and manage cases, reducing the risk of future outbreaks. Additionally, we worked alongside community leaders to educate at-risk populations on prevention, treatment, and the common stigma surrounding Yaws and similar diseases.
Breaking the Cycle & Taking Action
Neglected tropical diseases like Yaws persist in impoverished regions due to limited healthcare access and awareness. By expanding treatment programs, improving education, and strengthening healthcare systems, we can work toward eliminating Yaws entirely. The WHO has set an ambitious goal to eradicate Yaws by 2030, a goal that can be achieved through continued collaboration, advocacy, and investment in community-based healthcare solutions.
Yaws is preventable and treatable, yet thousands of children continue to suffer from its effects. By supporting organizations like Effect Hope, advocating for increased global health funding, and raising awareness, we can help eradicate this life-altering disease. Will you join us?


